Supercritical fluid chromatography (SFC) has traditionally been viewed as a powerful tool for chiral separations. Recent research shows a surge in SFC being used for achiral applications, particularly in the pharmaceutical sector.
We will compare chromatographic methods for analysis of oligonucleotides and mRNA, LC MS applications, and software. We will discuss the optimization of LC resolution, impact of melting temperature on siRNA analysis, non-specific adsorption of nucleic acid on column metal hardware, and new SEC column. Selected applications for phosphorothioate oligonucleotides and sgRNA analysis will be discussed.
Your HPLC workflow can be optimized and automated when characterizing monoclonal antibodies. In this presentation, we will walk through a new offering that is plug-and-play with all existing LCs and is robust and reproducible.
A truly universal chromatographic detector remains one of the most sought-after tools by analytical scientists. Professor James Grinias of Rowan University will describe the efforts of his laboratory on adopting Charged Aerosol Detection as a way of achieving such detection.
